Reddy M V, Malhotra A, Harinath B C
J Helminthol. 1984 Sep;58(3):259-62. doi: 10.1017/s0022149x00027103.
The utility of the IgG fraction of human filarial serum immunoglobulin in detecting circulating antigen by sandwich enzyme linked immunosorbent assay (ELISA) was studied. 27 of 33 sera from persons with microfilaraemia, 19 of 30 sera from clinical cases of filariasis, 4 of 30 sera from normal persons from a region endemic for filariasis showed the presence of circulating filarial antigen. All the 20 normal sera from the area where filariasis was not endemic gave negative reaction for filarial antigen. Those sera from persons with microfilaraemia that showed the presence of circulating antigen also showed an apparent positive correlation between the microfilarial density and the antigen titre.
研究了人丝虫血清免疫球蛋白IgG组分通过夹心酶联免疫吸附测定（ELISA）检测循环抗原的效用。33例微丝蚴血症患者的血清中有27例、30例丝虫病临床病例的血清中有19例、来自丝虫病流行地区的30例正常人的血清中有4例显示存在循环丝虫抗原。来自非丝虫病流行地区的所有20例正常血清对丝虫抗原均呈阴性反应。那些显示存在循环抗原的微丝蚴血症患者的血清，其微丝蚴密度与抗原滴度之间也呈现明显的正相关。
