Lerwick E
Surg Gynecol Obstet. 1983 Jan;156(1):51-5.
Preclinical animal studies have clearly indicated that dyed and undyed polydioxanone monofilament absorbable sutures have prolonged breaking strength retention, a reliable absorption profile and minimal tissue reaction. The suture provides wound support throughout extended postoperative periods and is most useful in those situations in which prolonged suture integrity is desirable. Based upon these clinical studies, polydioxanone monofilament absorbable sutures must be considered as a reliable, easy to use suture material which fulfills all performance criteria. The over-all clinical results were excellent. Polydioxanone was rated as significantly superior to gut in every category evaluated. The results of this study support the claim that polydioxanone monofilament absorbable sutures are the suture of choice for general surgical use as well as in a variety of other clinical applications in which an absorbable suture is required.
临床前动物研究已明确表明，染色和未染色的聚二氧杂环己酮单丝可吸收缝线具有延长的抗张强度保留时间、可靠的吸收特性和最小的组织反应。该缝线在术后较长时间内为伤口提供支撑，在需要延长缝线完整性的情况下最为有用。基于这些临床研究，聚二氧杂环己酮单丝可吸收缝线必须被视为一种可靠、易于使用且符合所有性能标准的缝线材料。总体临床结果非常出色。在评估的每个类别中，聚二氧杂环己酮的评分均显著优于肠线。这项研究的结果支持了以下观点：聚二氧杂环己酮单丝可吸收缝线是普通外科手术以及各种其他需要可吸收缝线的临床应用中的首选缝线。
