Ray J A, Doddi N, Regula D, Williams J A, Melveger A
Surg Gynecol Obstet. 1981 Oct;153(4):497-507.
The chemical and biologic properties of a unique, new monofilament suture, polydioxanone, have been described. The inherent flexibility of its polymer allows the polydioxanone suture to be fabricated into a monofilament fiber useful for all sizes of sutures. Polydioxanone suture has greater pliability than polypropylene suture and has greater strength than that of other monofilament sutures. In the body, polydioxanone suture retains its strength for longer periods than other synthetic absorbable sutures--58 per cent versus 1 to 5 per cent at four weeks and 14 per cent versus zero per cent at eight weeks, respectively. It elicits a low order of tissue response and is absorbed by simple hydrolysis.
一种独特的新型单丝缝线——聚二氧六环酮的化学和生物学特性已被描述。其聚合物固有的柔韧性使聚二氧六环酮缝线能够制成适用于各种尺寸缝线的单丝纤维。聚二氧六环酮缝线比聚丙烯缝线更柔韧，且比其他单丝缝线强度更大。在体内，聚二氧六环酮缝线比其他合成可吸收缝线保持强度的时间更长——四周时分别为58% 对比1% 至5%，八周时分别为14% 对比0%。它引起的组织反应程度较低，并且通过简单水解被吸收。
