Löfgren O, Andersson D
J Perinat Med. 1983;11(1):51-6. doi: 10.1515/jpme.1983.11.1.51.
Continuous transcutaneous carbon dioxide partial pressure (tc PCO2) and continuous transcutaneous oxygen partial pressure (tc PO2) was monitored simultaneously in 10 consecutive neonatal intensive care patients treated for respiratory problems or immaturity. During measurement the electrode temperature was 44 degrees C while during the resting periods--with the electrodes left in situ--the electrode temperature was 37 degrees C. Measurements were performed for periods up to 31 hours. It was possible to discover changes in central blood gas partial pressures also at the lower electrode temperature. This was especially true for the tc PCO2 recording which was less influenced by the decrease in electrode temperature than the tc PO2 recording. In six patients an increased frequency of apnoea was diagnosed by the transcutaneous blood gas monitoring equipment previous to other clinical signs. A statistically highly significant correlation was found between transcutaneous and arterial blood gas values, the arterial samples obtained from umbilical artery catheters. tc PCO2 and tc PO2 very sensitively reacts to changes in the breathing pattern and to changes in activity of the neonate emphasizing the drawbacks of previous blood gas monitoring techniques. The technique for continuous transcutaneous carbon dioxide monitoring is ready for clinical use and is a valuable additional tool in all neonatal intensive care patients with the risk of alveolar hypoventilation.
对10例因呼吸问题或发育不成熟而接受治疗的新生儿重症监护患者连续同时监测经皮二氧化碳分压（tc PCO2）和经皮氧分压（tc PO2）。测量期间电极温度为44摄氏度，而在休息期间（电极留在原位）电极温度为37摄氏度。测量持续时间长达31小时。在较低的电极温度下也能够发现中心血气分压的变化。对于tc PCO2记录尤其如此，其受电极温度降低的影响小于tc PO2记录。在6例患者中，经皮血气监测设备在出现其他临床体征之前诊断出呼吸暂停频率增加。在经皮和动脉血气值之间发现了统计学上高度显著的相关性，动脉样本取自脐动脉导管。tc PCO2和tc PO2对新生儿呼吸模式的变化和活动变化非常敏感，这突出了以往血气监测技术的缺点。连续经皮二氧化碳监测技术已准备好用于临床，是所有有肺泡通气不足风险的新生儿重症监护患者的一种有价值的辅助工具。
