George C F, Waters W E, Nicholas J A
Br Med J (Clin Res Ed). 1983 Oct 22;287(6400):1193-6. doi: 10.1136/bmj.287.6400.1193.
Leaflets containing information about medicines were issued to 56 patients prescribed penicillins and 43 patients prescribed non-steroidal anti-inflammatory drugs. The patients were interviewed between four and 10 days later and their responses compared with those of 65 patients prescribed penicillin and 33 prescribed nonsteroidal anti-inflammatory drugs who did not receive a leaflet. Patients who received a leaflet were more likely to be completely satisfied with their treatment and with the information they had been given. They were also more likely to know the name of their medicine and much more aware of potential unwanted effects. Although there was no evidence that knowledge increased the incidence of adverse effects, when these did occur they were more likely to be recognised as being due to the medicine. Further studies of other leaflets are warranted, including leaflets for drugs that are taken long term.
向56名开具青霉素处方的患者和43名开具非甾体抗炎药处方的患者发放了包含药品信息的传单。在四到十天后对这些患者进行了访谈,并将他们的回答与65名开具青霉素处方且未收到传单的患者以及33名开具非甾体抗炎药处方且未收到传单的患者的回答进行了比较。收到传单的患者对治疗及其所获得的信息更有可能完全满意。他们也更有可能知道所服用药物的名称,并且对潜在的不良反应有更多的了解。虽然没有证据表明知识会增加不良反应的发生率,但当不良反应确实发生时,它们更有可能被识别为是由药物引起的。有必要对其他传单进行进一步研究,包括针对长期服用药物的传单。