Gibbs S, Waters W E, George C F
Clinical Pharmacology Group, University of Southampton, Bassett Crescent East.
J R Soc Med. 1990 May;83(5):292-7. doi: 10.1177/014107689008300505.
Three thousand four hundred and ten patients recruited at 254 pharmacies took part in a national postal survey of the effect of prescription information leaflets. The patients had been prescribed penicillins, non-steroidal anti-inflammatory drugs (NSAIDs) or beta-adrenoceptor antagonists. The 1809 patients who received leaflets knew more about their medicines, especially the side effects and were significantly more satisfied than the 1601 patients who were not given additional written information. The leaflets were found to be effective when issued in the north, in the south and in small, medium and large towns. Patients of both sexes, all age groups and social classes were found to benefit from the leaflets and almost everyone (97%) thought they were a good idea. These results confirm and extend our previous findings and add further support for the routine use of information leaflets with prescribed medicines.
在254家药店招募的3410名患者参与了一项关于处方信息单效果的全国性邮寄调查。这些患者被开具了青霉素、非甾体抗炎药（NSAIDs）或β-肾上腺素能受体拮抗剂。收到信息单的1809名患者对自己的药物了解更多，尤其是副作用方面，并且比未收到额外书面信息的1601名患者满意度显著更高。研究发现，信息单在北方、南方以及大、中、小城镇发放时均有效。各个性别、年龄组和社会阶层的患者都从信息单中受益，几乎所有人（97%）都认为这是个好主意。这些结果证实并扩展了我们之前的发现，为在处方药中常规使用信息单提供了进一步支持。
