Van Thiel D H, Gavaler J S, Cobb C F, Santucci L, Graham T O
Pharmacol Biochem Behav. 1983;18 Suppl 1:317-23. doi: 10.1016/0091-3057(83)90193-4.
The available evidence which suggests that ethanol is a Leydig cell toxin is presented. Both in vivo and in vitro data are reviewed. The minor differences obtained in vitro as compared to those obtained in vivo are discussed. As a result of information obtained during the last decade, there can be little doubt that ethanol and possibly acetaldehyde are clinically important environmental Leydig cell toxins.
现有证据表明乙醇是一种睾丸间质细胞毒素。本文综述了体内和体外数据，并讨论了体外与体内所得结果的细微差异。根据过去十年获得的信息，毫无疑问乙醇以及可能还有乙醛是临床上重要的环境性睾丸间质细胞毒素。
