Aspergillus endophthalmitis in an intravenous drug user.

A 27-year-old male drug user administered methamphetamine hydrochloride solution intravenously (IV) from a storage vial. Within two weeks he was admitted with a fungal endophthalmitis of the right eye. A diagnostic and therapeutic vitrectomy was performed. Aspergillus fumigatus was cultured from the drug storage vial and the vitreous biopsy specimen. The endophthalmitis was not controlled by IV and intravitreal amphotericin B. Pathological examination revealed fungal abscesses in the vitreous and subretinal space.