Singletary K W, Milner J A, Martin S E
Mutat Res. 1984 Mar;126(1):19-24. doi: 10.1016/0027-5107(84)90165-9.
These studies describe the influence of dietary protein concentration on the ability of rat-liver postmitochondrial fraction (S9) to mediate 7,12-dimethylbenz[a]anthracene (DMBA) mutagenicity in the Ames Salmonella/microsome assay. A negative correlation was observed between dietary protein content and DMBA mutagenicity. The effect of protein was not dependent on the quantity of Aroclor used for induction. Dietary protein did not influence the mutagenicity of DMBA when isolated microsomes were used in place of S9.
这些研究描述了膳食蛋白质浓度对大鼠肝脏线粒体后组分（S9）在艾姆斯沙门氏菌/微粒体试验中介导7,12-二甲基苯并[a]蒽（DMBA）致突变性能力的影响。观察到膳食蛋白质含量与DMBA致突变性之间呈负相关。蛋白质的作用不依赖于用于诱导的多氯联苯混合物的量。当使用分离的微粒体代替S9时，膳食蛋白质不影响DMBA的致突变性。
