Adams L, Lonsdale D, Robinson M, Rawbone R, Guz A
Br Med J (Clin Res Ed). 1984 Mar 24;288(6421):891-5. doi: 10.1136/bmj.288.6421.891.
A longitudinal study was carried out from 1975 to 1979 in a cohort of 405 secondary school children. At yearly intervals they underwent a series of tests of pulmonary function designed to monitor lung development; some of these tests are relatively sensitive indicators of early abnormalities. A self administered questionnaire provided details of smoking habits and respiratory symptoms. The prevalence of smoking increased with age; most of those smoking at 16 had already been smoking, at least experimentally, at 13. Taking up smoking was clearly associated with the early onset of cough, production of phlegm, and shortness of breath on exertion. After two years of smoking more than a few cigarettes a day the children who smoked appeared considerably less healthy than their non-smoking peers and showed some evidence of early obstruction of the airways.
1975年至1979年对405名中学生进行了一项纵向研究。他们每年接受一系列旨在监测肺部发育的肺功能测试;其中一些测试是早期异常的相对敏感指标。一份自我填写的问卷提供了吸烟习惯和呼吸道症状的详细信息。吸烟率随年龄增长而上升;大多数16岁吸烟的人在13岁时就已经开始吸烟,至少是尝试性吸烟。开始吸烟显然与咳嗽、咳痰和运动时气短的早期发作有关。每天吸几支烟两年后,吸烟的孩子看起来明显不如不吸烟的同龄人健康,并且有一些气道早期阻塞的迹象。