Lox C D
Ecotoxicol Environ Saf. 1984 Jun;8(3):280-3. doi: 10.1016/0147-6513(84)90031-9.
Male Sprague-Dawley rats were placed on a drinking solution containing either 10 parts per million (ppm) carbaryl or water for 30 days. Plasma was analyzed for the prothrombin time, partial thromboplastin time, fibrinogen, and clotting factor activity for coagulation factors II, V, VII, VIII, IX, X, XII and the platelet count. Only two hematological parameters measured were statistically different from the controls; these parameters were the platelet count and factor VII activity, both of which were reduced. Histological examination of the hepatic tissue illustrated that a number of pathological changes were occurring.
将雄性斯普拉格-道利大鼠置于含有百万分之十（ppm）西维因或水的饮用溶液中30天。分析血浆中的凝血酶原时间、部分凝血活酶时间、纤维蛋白原以及凝血因子II、V、VII、VIII、IX、X、XII的凝血因子活性和血小板计数。所测量的血液学参数中只有两项与对照组有统计学差异；这些参数是血小板计数和因子VII活性，两者均降低。肝组织的组织学检查表明正在发生一些病理变化。
