Lox C D
Ecotoxicol Environ Saf. 1983 Oct;7(5):451-4. doi: 10.1016/0147-6513(83)90084-2.
Male Sprague-Dawley rats were treated with 1 ml of diazinon or malathion, 1750 ppm given orally by gavage. Clotting determinations included the prothrombin time, partial thromboplastin time, fibrinogen, and coagulation factors II, V, VII, and X, plus the hematocrit and platelet count. The results suggest that insecticides influence the clotting times of rats ingesting these insecticides even after as short a time span as 2 hr.
雄性斯普拉格-道利大鼠经口灌胃给予1毫升二嗪农或马拉硫磷,剂量为1750 ppm。凝血测定包括凝血酶原时间、部分凝血活酶时间、纤维蛋白原、凝血因子II、V、VII和X,以及血细胞比容和血小板计数。结果表明,即使在短至2小时的时间段后,杀虫剂也会影响摄入这些杀虫剂的大鼠的凝血时间。