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短期乙醇摄入对大鼠血液凝固的影响。

The effects of short term ethanol consumption on blood coagulation in the rat.

作者信息

Lox C D

出版信息

Gen Pharmacol. 1982;13(1):57-8. doi: 10.1016/0306-3623(82)90012-x.

DOI:10.1016/0306-3623(82)90012-x
PMID:7060922
Abstract
  1. Female Sprague-Dawley rats were placed on water (controls) or 10% ethanol (ETOH) for 14 days. A second group of ETOH treated rats were removed from ETOH and placed on water for 7 days. 2. Plasma samples were assayed for various coagulation factors following treatment. 3. Following 2 weeks of ETOH, significant differences were noted for fibrinogen, the platelet count and factors V, VII, VIII, X and XII. After 1 weeks' removal from ETOH, differences were still noted for the platelet count, fibrinogen and factors VII, VIII and XII.
摘要
  1. 将雌性斯普拉格-道利大鼠置于饮用水(对照组)或10%乙醇(ETOH)中14天。第二组经ETOH处理的大鼠从ETOH中取出,置于饮用水中7天。2. 处理后测定血浆样本中的各种凝血因子。3. 给予ETOH 2周后,纤维蛋白原、血小板计数以及因子V、VII、VIII、X和XII有显著差异。从ETOH中取出1周后,血小板计数、纤维蛋白原以及因子VII、VIII和XII仍有差异。

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