槲皮素对特应性毒素促进7,12-二甲基苯并[a]蒽引发的小鼠皮肤乳头瘤形成作用的抑制。
Inhibition by quercetin of the promoting effect of teleocidin on skin papilloma formation in mice initiated with 7,12-dimethylbenz[a]anthracene.
作者信息
Nishino H, Iwashima A, Fujiki H, Sugimura T
出版信息
Gan. 1984 Feb;75(2):113-6.
PMID:6428958
Abstract
Quercetin markedly suppressed the promoting effect of teleocidin on skin tumor formation in mice initiated with 7,12-dimethylbenz[a]anthracene. This activity of quercetin may have some bearing on the fact that quercetin is not carcinogenic despite showing mutagenicity.
摘要
槲皮素显著抑制了杀鱼菌素对用7,12-二甲基苯并[a]蒽引发的小鼠皮肤肿瘤形成的促进作用。槲皮素的这种活性可能与以下事实有关：尽管槲皮素具有致突变性，但它并不具有致癌性。
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