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相似文献

1
Are HLA antigens important in the development of alcohol-induced liver disease?人类白细胞抗原（HLA）抗原在酒精性肝病的发展过程中重要吗？
Br Med J (Clin Res Ed). 1982 Aug 21;285(6341):533-4. doi: 10.1136/bmj.285.6341.533.
2
[Prevalence of HLA-A and -B antigens, anti-HBc and -HBs antibodies in alcoholic hepatopathies].
Ann Med Interne (Paris). 1985;136(3):225-8.
3
HLA antigens in alcoholics, with special reference to alcoholic cirrhosis.酗酒者的人类白细胞抗原，特别提及酒精性肝硬化
Scand J Gastroenterol. 1980;15(4):453-6. doi: 10.3109/00365528009181499.
4
Association between HLA-B40 and acute alcoholic hepatitis with cirrhosis and the lack of relation between carcinoembryonic antigen and HLA antigens in alcoholic liver disease.HLA - B40与急性酒精性肝炎伴肝硬化之间的关联以及癌胚抗原与酒精性肝病中HLA抗原之间不存在关联。
Scand J Gastroenterol. 1983 Mar;18(2):267-71. doi: 10.3109/00365528309181593.
5
Histocompatibility antigens in patients with alcoholic liver disease in Scotland and northeastern England: failure to show an association.苏格兰和英格兰东北部酒精性肝病患者的组织相容性抗原：未显示出相关性。
Gut. 1988 Feb;29(2):146-8. doi: 10.1136/gut.29.2.146.
6
Histocompatibility antigens: markers of susceptibility to and protection from alcoholic liver disease in a Portuguese population.组织相容性抗原：葡萄牙人群中酒精性肝病易感性和保护性的标志物。
Hepatology. 1988 May-Jun;8(3):455-8. doi: 10.1002/hep.1840080303.
7
[Prevalence of markers correlated with the hepatitis B virus in patients with alcoholic hepatopathy].[酒精性肝病患者中与乙型肝炎病毒相关标志物的患病率]
G Clin Med. 1982 Oct;63(10):688-98.
8
Distribution of HLA histocompatibility antigens, ABO blood groups and Rh antigens in alcoholic liver disease.HLA组织相容性抗原、ABO血型及Rh抗原在酒精性肝病中的分布
Gut. 1979 Apr;20(4):288-90. doi: 10.1136/gut.20.4.288.
9
[The importance of HLA antigens in alcoholic cirrhosis].
Acta Gastroenterol Latinoam. 1985;15(3):133-40.
10
HLA types in liver disease in the West of Ireland.爱尔兰西部肝病中的人类白细胞抗原类型
Ir J Med Sci. 1980 Feb;149(2):63-5. doi: 10.1007/BF02939113.

引用本文的文献

1
Global prevalence, incidence, and outcomes of alcohol related liver diseases: a systematic review and meta-analysis.全球酒精相关性肝病的患病率、发病率和结局：系统评价和荟萃分析。
BMC Public Health. 2023 May 11;23(1):859. doi: 10.1186/s12889-023-15749-x.
2
Liver disease in the alcoholic.酗酒者的肝脏疾病
Can Fam Physician. 1986 Sep;32:1938-89.
3
Role of body mass index in the prediction of all cause mortality in over 62,000 men and women. The Italian RIFLE Pooling Project. Risk Factor and Life Expectancy.体重指数在62000多名男性和女性全因死亡率预测中的作用。意大利RIFLE汇总项目。风险因素与预期寿命。
J Epidemiol Community Health. 1998 Jan;52(1):20-6. doi: 10.1136/jech.52.1.20.
4
Blood group lewis phenotype on erythrocytes and in saliva in alcoholic pancreatitis and chronic liver disease.酒精性胰腺炎和慢性肝病患者红细胞及唾液中的血型Lewis表型
J Clin Pathol. 1984 Jul;37(7):778-82. doi: 10.1136/jcp.37.7.778.
5
Alcoholic liver disease in the 1980s.20世纪80年代的酒精性肝病。
Br Med J (Clin Res Ed). 1983 Dec 17;287(6408):1819-21. doi: 10.1136/bmj.287.6408.1819.
6
Measuring the damage--ethanol and the liver.测量损伤——乙醇与肝脏
Gut. 1986 Jul;27(7):751-5. doi: 10.1136/gut.27.7.751.
7
Histocompatibility antigens in patients with alcoholic liver disease in Scotland and northeastern England: failure to show an association.苏格兰和英格兰东北部酒精性肝病患者的组织相容性抗原：未显示出相关性。
Gut. 1988 Feb;29(2):146-8. doi: 10.1136/gut.29.2.146.
8
Genetic predisposition to alcoholic liver disease.酒精性肝病的遗传易感性。
Gut. 1992 Nov;33(11):1444-7. doi: 10.1136/gut.33.11.1444.

本文引用的文献

1
MICRODROPLET ASSAY OF HUMAN SERUM CYTOTOXINS.人血清细胞毒素的微滴分析法
Nature. 1964 Dec 5;204:998-1000. doi: 10.1038/204998b0.
2
The estimation and significance of the logarithm of a ratio of frequencies.频率比的对数的估计及其意义。
Ann Hum Genet. 1956 May;20(4):309-11. doi: 10.1111/j.1469-1809.1955.tb01285.x.
3
[HLA groups in cirrhotic alcoholic patients].[肝硬化酒精性患者的人类白细胞抗原组]
Nouv Presse Med. 1980 Mar 1;9(10):712.
4
Serological markers of hepatitis B in patients with alcoholic liver disease: a multi-centre survey.酒精性肝病患者的乙肝血清学标志物：一项多中心调查。
J Clin Pathol. 1981 Sep;34(9):1017-9. doi: 10.1136/jcp.34.9.1017.
5
Aldehyde dehydrogenase deficiency as cause of facial flushing reaction to alcohol in Japanese.醛脱氢酶缺乏是日本人饮酒后面部潮红反应的原因。
Lancet. 1981 Oct 31;2(8253):982. doi: 10.1016/s0140-6736(81)91172-7.
6
Ethanol increases hepatic smooth endoplasmic reticulum and drug-metabolizing enzymes.
Science. 1968 Mar 29;159(3822):1469-70. doi: 10.1126/science.159.3822.1469.
7
Hepatic microsomal enzymes in man and rat: induction and inhibition by ethanol.人和大鼠的肝微粒体酶：乙醇的诱导和抑制作用
Science. 1968 Nov 8;162(3854):690-1. doi: 10.1126/science.162.3854.690.
8
Alcohol-drugs interaction in man: alcohol and tolbutamide.
Eur J Clin Invest. 1971 Sep;1(6):421-4. doi: 10.1111/j.1365-2362.1971.tb00552.x.
9
Lymphocyte transformation and alcoholic liver injury.淋巴细胞转化与酒精性肝损伤。
Gastroenterology. 1972 Dec;63(6):1020-5.
10
In vitro and in vivo studies of cellular immunity in alcoholic cirrhosis.酒精性肝硬化细胞免疫的体外和体内研究
Am J Dig Dis. 1974 Mar;19(3):199-205. doi: 10.1007/BF01072535.

人类白细胞抗原（HLA）抗原在酒精性肝病的发展过程中重要吗？

Are HLA antigens important in the development of alcohol-induced liver disease?

作者信息

Faizallah R, Woodrow J C, Krasner N K, Walker R J, Morris A I

出版信息

Br Med J (Clin Res Ed). 1982 Aug 21;285(6341):533-4. doi: 10.1136/bmj.285.6341.533.

DOI:10.1136/bmj.285.6341.533
PMID:6809159
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1499051/
Abstract

The prevalences of 10 HLA-A and 16 HLA-B antigens were determined in 50 patients with alcoholic cirrhosis and 120 alcoholic patients without cirrhosis and compared with those in a control group of 550 healthy subjects from the same geographical area. B40 was absent in the patients with cirrhosis but was found in 18 (15%) of the patients without cirrhosis (p = 0.0087). No other association was noted. It is concluded that there is no good evidence to date of an association between HLA antigen state and susceptibility to alcohol-induced cirrhosis.

摘要

在50例酒精性肝硬化患者和120例无肝硬化的酒精性患者中测定了10种HLA - A和16种HLA - B抗原的流行率，并与来自同一地理区域的550名健康受试者组成的对照组进行比较。肝硬化患者中不存在B40，但在无肝硬化的患者中有18例（15%）发现有B40（p = 0.0087）。未发现其他关联。结论是，迄今为止，没有充分证据表明HLA抗原状态与酒精性肝硬化易感性之间存在关联。