Strachan A F, Noakes T D, Kotzenberg G, Nel A E, de Beer F C
Br Med J (Clin Res Ed). 1984 Nov 10;289(6454):1249-51. doi: 10.1136/bmj.289.6454.1249.
Long distance runners competing in events ranging from 15 to 88 km showed a distance related acute phase response as indicated by significantly raised serum C reactive protein concentrations. In trained athletes only a small rise in C reactive protein concentrations was seen after races of less than 21 km. After an 88 km ultramarathon concentrations comparable to those found in patients with small myocardial infarctions were detected. Indomethacin did not affect the increases in C reactive protein after the ultramarathon. This study has established serial C reactive protein concentrations for given race distances. These data may help in diagnosing myocardial infarction during long distance running. The acute phase response should be measured in untrained people running shorter distances to provide comparative data for the physically untrained population.
参加15至88公里赛事的长跑运动员表现出与距离相关的急性期反应,血清C反应蛋白浓度显著升高表明了这一点。在训练有素的运动员中,21公里以下的比赛后C反应蛋白浓度仅有小幅升高。在一场88公里的超级马拉松赛后,检测到的C反应蛋白浓度与小型心肌梗死患者相当。消炎痛对超级马拉松赛后C反应蛋白的升高没有影响。本研究确定了特定比赛距离下的C反应蛋白浓度序列。这些数据可能有助于在长跑过程中诊断心肌梗死。对于短距离跑步的非训练人群,应测量急性期反应,以便为缺乏体育锻炼的人群提供对比数据。