Murthy K K, Ragland W L
Vet Immunol Immunopathol. 1984 Oct;7(3-4):347-57. doi: 10.1016/0165-2427(84)90092-8.
Carrageenan treatment of chickens resulted in splenomegaly and enlargement of bursa but had no effect on the thymus. The dose and route of administration had a profound effect on humoral immune response to Brucella abortus and sheep red blood cells. Antibody response to B. abortus was either unaffected or significantly enhanced, whereas response to red blood cells was severely suppressed. Furthermore, delineation of the class of antibody response affected by the treatment, using 2-mercaptoethanol, suggested that there was a selective inhibition of IgG response to the T dependent antigen.
用角叉菜胶处理鸡会导致脾脏肿大和法氏囊增大，但对胸腺没有影响。给药剂量和途径对鸡对布鲁氏菌和绵羊红细胞的体液免疫反应有深远影响。对布鲁氏菌的抗体反应要么未受影响，要么显著增强，而对红细胞的反应则受到严重抑制。此外，使用2-巯基乙醇对受该处理影响的抗体反应类别进行的描述表明，对T细胞依赖性抗原的IgG反应存在选择性抑制。
