锌诱导的对镉改变药物作用的保护作用。
Zinc-induced protection against cadmium alteration of drug action.
作者信息
Early J L, Schnell R C
出版信息
Res Commun Chem Pathol Pharmacol. 1978 Feb;19(2):369-72.
PMID:644129
Abstract
Pretreatment of male rats with cadmium acetate potentiates the duration of hexobarbital hypnosis and inhibits the rate of hepatic microsomal drug metabolism. Pretreatment of rats with zinc acetate protects against these alterations in drug action elicited by cadmium.
摘要
用醋酸镉对雄性大鼠进行预处理会增强己巴比妥催眠的持续时间，并抑制肝微粒体药物代谢速率。用醋酸锌对大鼠进行预处理可防止镉引起的这些药物作用改变。
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