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1
Suppressor activity of blood lymphocytes from guinea-pigs treated with ALS.用抗淋巴细胞血清处理的豚鼠血液淋巴细胞的抑制活性
Immunology. 1980 Mar;39(3):435-40.
2
Bone marrow cells that prolong graft survival in ALS-treated mice: suppressor activity in mixed cell culture.在经抗淋巴细胞血清(ALS)处理的小鼠中能延长移植物存活时间的骨髓细胞:混合细胞培养中的抑制活性
Transplant Proc. 1989 Feb;21(1 Pt 1):228-30.
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Production of a suppressor factor by adherent cells from Mycobacterium tuberculosis-infected guinea-pigs.结核分枝杆菌感染的豚鼠的贴壁细胞产生抑制因子。
Clin Exp Immunol. 1981 Aug;45(2):427-32.
4
Effect of phytohemagglutinin (PHA) and anti-lymphocyte sera (ALS) on the activity of bêta-glucuronidase in human lymphocyte cultures.植物血凝素(PHA)和抗淋巴细胞血清(ALS)对人淋巴细胞培养物中β-葡萄糖醛酸酶活性的影响。
Biomedicine. 1973 Jul;18(4):354-63.
5
RATG treatment induces suppressor cells in primates.RATG治疗可在灵长类动物中诱导产生抑制性细胞。
Transplant Proc. 1991 Feb;23(1 Pt 1):302-4.
6
Effect of actinomycin C and ALS on the ability to transfer delayed hypersensitivity to protein by guinea-pig lymphocytes.放线菌素C和抗淋巴细胞血清对豚鼠淋巴细胞传递对蛋白质的迟发型超敏反应能力的影响。
Bull Acad Pol Sci Biol. 1974;22(3):167-71.
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[Evaluation of the protective action of diphosphonic compounds against a T-lymphocyte lesion by antilymphocyte serum].[二膦酸化合物对抗淋巴细胞血清所致T淋巴细胞损伤的保护作用评估]
Biull Eksp Biol Med. 1979 Mar;87(3):259-60.
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[Stimulation of peripheral guinea pig blood lymphocytes by autologous epidermal cells].[自体表皮细胞对豚鼠外周血淋巴细胞的刺激作用]
C R Seances Acad Sci D. 1979 Nov 26;289(14):1041-4.
9
Generation of suppressor cells by administration of deaggregated horse anti-human thymocyte globulin in man.在人体中通过给予去聚合的马抗人胸腺细胞球蛋白产生抑制细胞。
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The immunologic function of 1B2+ double negative (CD4-CD8-) T cells in the 2C transgenic mouse.2C转基因小鼠中1B2 +双阴性(CD4-CD8-)T细胞的免疫功能
J Surg Res. 2005 Jun 15;126(2):160-6. doi: 10.1016/j.jss.2005.01.018.

本文引用的文献

1
Lymphocyte activation. I. Response of T and B lymphocytes to phytomitogens.淋巴细胞活化。I. T淋巴细胞和B淋巴细胞对植物有丝分裂原的反应。
Clin Exp Immunol. 1971 Oct;9(4):483-98.
2
The effect of heterologous anti-lymphocytic serum on the small lymphocyte population of rats.异种抗淋巴细胞血清对大鼠小淋巴细胞群体的影响。
J Exp Med. 1968 Jul 1;128(1):111-9. doi: 10.1084/jem.128.1.111.
3
Characterisation and separation of mouse lymphocyte subpopulations responding to phytohemagglutinin and pokeweed mitogens.对响应植物血凝素和商陆有丝分裂原的小鼠淋巴细胞亚群的表征与分离。
Cell Immunol. 1973 Jan;6(1):25-40. doi: 10.1016/0008-8749(73)90003-8.
4
Prolongation of allograft survival in mice by administration of anti-Thy 1 serum. I. Mediation by in vivo activation of regulatory T cells.通过给予抗Thy 1血清延长小鼠同种异体移植物存活时间。I. 体内调节性T细胞激活的介导作用
J Immunol. 1975 Jul;115(1):1-4.
5
Suppressor activity of splenocytes from mice treated with Ecteinascidia turbinata extract.被海鞘提取物处理过的小鼠脾细胞的抑制活性。
J Immunol. 1979 Jan;122(1):8-11.
6
Role of adherent cells in immune responses to phytohemagglutinin and concanavalin A.黏附细胞在对植物血凝素和伴刀豆球蛋白A免疫反应中的作用。
Eur J Immunol. 1978 Feb;8(2):77-81. doi: 10.1002/eji.1830080202.

用抗淋巴细胞血清处理的豚鼠血液淋巴细胞的抑制活性

Suppressor activity of blood lymphocytes from guinea-pigs treated with ALS.

作者信息

Rudnicka W

出版信息

Immunology. 1980 Mar;39(3):435-40.

PMID:6449472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1457794/
Abstract

PHA-induced transformation of guinea-pig lymphocytes was profoundly inhibited by the injection of antilymphocyte serum (ALS). This effect, seen 24 h after ALS administration, disappeared within 3 days. Lymphocytes of animals injected with ALS 24 h earlier inhibited the blast transformation of autologous normal lymphocytes. The supernatants of short term cultures of such cells, even after pre-treatment with puromycin, exhibited the same inhibitory activity. It is suggested that the immunosuppressive effect of ALS is not limited to its direct action on lymphocytes.

摘要

注射抗淋巴细胞血清(ALS)可显著抑制PHA诱导的豚鼠淋巴细胞转化。这种效应在给予ALS后24小时出现,3天内消失。提前24小时注射ALS的动物的淋巴细胞抑制了自体正常淋巴细胞的母细胞转化。即使在用嘌呤霉素预处理后,这些细胞短期培养的上清液仍表现出相同的抑制活性。提示ALS的免疫抑制作用不限于其对淋巴细胞的直接作用。