Soutter W P, Sharp F, Clark D M
Br J Anaesth. 1978 May;50(5):445-50. doi: 10.1093/bja/50.5.445.
A new instrument for the measurement of lactate in biological fluids, the Lactate Analyzer 640, has been evaluated. The method of use recommended by the manufacturer for blood samples was found to be inadequate. A new method of sample preparation for the instrument, based upon immediate haemolysis and fluoridation of blood, has been developed, allowing measurement of whole blood lactate concentration to be performed on samples as small as 150 microlitre within 5 min of withdrawal. The instrument is designed to be operated by a medical practitioner. Excellent correlation with a conventional enzymatic assay was found. These features make this new method particularly applicable to rapidly changing clinical situations such as shock in adult patients, asphyxia neonatorum and intrapartum foetal hypoxia.
一种用于测量生物体液中乳酸的新仪器——乳酸分析仪640已得到评估。发现制造商推荐的用于血样的使用方法并不充分。基于血液的即时溶血和氟化作用，已开发出一种该仪器的新样品制备方法，使得能在采血后5分钟内对小至150微升的样品进行全血乳酸浓度测量。该仪器设计为由医生操作。发现其与传统酶法测定具有极好的相关性。这些特性使得这种新方法特别适用于快速变化的临床情况，如成年患者的休克、新生儿窒息和分娩期胎儿缺氧。
