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酒精性肝硬化和胰腺炎患者的饮酒模式与血脂:一项对比研究。

Alcohol consumption pattern and serum lipids in alcoholic cirrhosis and pancreatitis. A comparative study.

作者信息

Stigendal L, Olsson R

出版信息

Scand J Gastroenterol. 1984 Jul;19(5):582-7.

PMID:6474079
Abstract

Drinking and dietary habits and serum lipids were studied in two groups of chronic alcoholics, one with liver cirrhosis and the other with acute or recurrent pancreatitis, with the intention of investigating whether these factors could be of importance for the seemingly haphazard occurrence of different organ damages in chronic alcoholics. Our data show that patients with alcoholic pancreatitis have a more intermittent drinking pattern than patients with alcoholic cirrhosis. The amount of alcohol required to cause pancreatitis seems to be smaller than what is necessary to produce cirrhosis. Although none of the cirrhotics had clinical symptoms of pancreatitis, 58% of the autopsied cirrhotics had some pancreatic damage at autopsy. It may be that symptomatic pancreatitis prevents the patients from drinking the larger amounts of alcohol necessary to produce cirrhosis. Dietary habits or occurrence of lipid abnormalities during abstinence did not differ between the groups.

摘要

对两组慢性酒精中毒患者的饮酒和饮食习惯以及血脂进行了研究,一组患有肝硬化,另一组患有急性或复发性胰腺炎,目的是调查这些因素是否可能对慢性酒精中毒患者不同器官损害看似随机发生具有重要意义。我们的数据表明,酒精性胰腺炎患者的饮酒模式比酒精性肝硬化患者更具间歇性。引发胰腺炎所需的酒精量似乎比引发肝硬化所需的量要小。虽然所有肝硬化患者均无胰腺炎的临床症状,但58% 的接受尸检的肝硬化患者在尸检时有一些胰腺损伤。可能是有症状的胰腺炎使患者无法饮用产生肝硬化所需的大量酒精。两组患者在戒酒期间的饮食习惯或脂质异常的发生情况并无差异。

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