Pitchumoni C S, Sonnenshein M, Candido F M, Panchacharam P, Cooperman J M
Am J Clin Nutr. 1980 Mar;33(3):631-6. doi: 10.1093/ajcn/33.3.631.
The pathogenesis of chronic alcoholic pancreatitis is unclear. Some European studies have shown that alcoholics who develop pancreatitis consume a diet richer in protein and fat than normal controls. The infrequency of alcoholic cirrhosis in patients with alcoholic pancreatitis in these studies was explained by this enhanced nutritional intake protecting the liver but not the pancreas. In this study we evaluated by an oral recall method the nutritional intake of patients with alcoholic pancreatitis or alcoholic cirrhosis prior to the onset of symptomatology and compared the data with established norms. Our data did not confirm the European observation that pancreatitis patients consume amounts of protein and fat, more than the general population and more than alcoholics with cirrhosis. Furthermore, the combined incidence of cirrhosis and pancreatitis was not infrequent. Our observations do not disprove that a high fat and/or protein diet predispose to pancreatitis but suggest that such a diet is not a prerequisite for alcoholics to develop pancreatitis.
慢性酒精性胰腺炎的发病机制尚不清楚。一些欧洲研究表明，患胰腺炎的酗酒者摄入的蛋白质和脂肪比正常对照组更多。这些研究中酒精性胰腺炎患者酒精性肝硬化发生率较低的原因是，这种增加的营养摄入对肝脏有保护作用，但对胰腺没有。在本研究中，我们通过口头回忆法评估了酒精性胰腺炎或酒精性肝硬化患者在症状出现前的营养摄入情况，并将数据与既定标准进行了比较。我们的数据并未证实欧洲的观察结果，即胰腺炎患者摄入的蛋白质和脂肪量比普通人群以及酒精性肝硬化患者更多。此外，肝硬化和胰腺炎的合并发生率并不低。我们的观察结果并未反驳高脂肪和/或高蛋白饮食易引发胰腺炎的观点，但表明这种饮食并非酗酒者患胰腺炎的必要条件。
