Jacoby R J
Z Gerontol. 1984 May-Jun;17(3):132-5.
The role of CT in the diagnosis of senile dementia of Alzheimer type (SDAT) is discussed. Research data show that, although SDAT is closely correlated with brain atrophy (sulcal and ventricular dilatation) there is a significant overlap with the normal elderly population: that is to say, within the demented population, CT changes correlate only weakly with cognitive impairment. However, taken together with other clinical indices, CT can be useful both for the assessment of SDAT and the exclusion of treatable lesions. Newer computer methods of analysis and technical improvements hold out hope for future clinical and research advances in this area.
本文讨论了CT在阿尔茨海默型老年痴呆（SDAT）诊断中的作用。研究数据表明，尽管SDAT与脑萎缩（脑沟和脑室扩张）密切相关，但在正常老年人群中也存在显著重叠：也就是说，在痴呆人群中，CT改变与认知障碍之间的相关性较弱。然而，结合其他临床指标，CT对于SDAT的评估以及排除可治疗病变均有帮助。更新的计算机分析方法和技术改进为该领域未来的临床和研究进展带来了希望。
