老年痴呆症与正常衰老的计算机断层扫描结果
Computed tomography findings in senile dementia and normal aging.
作者信息
Soininen H, Puranen M, Riekkinen P J
出版信息
J Neurol Neurosurg Psychiatry. 1982 Jan;45(1):50-4. doi: 10.1136/jnnp.45.1.50.
Computed tomography (CT) findings in 57 patients with senile dementia of Alzheimer type (SDAT), 19 patients with multi-infarct dementia and 85 controls of similar age and sex were studied. The SDAT patients differed from the controls of ventricular dilatation, frontal horn index, cella media index and the width of the third ventricle, and also in the index of cortical atrophy. Even the least severely demented SDAT patients differed from the controls. In the SDAT group with the increasing degree of intellectual impairment the ventricular dilatation increased, but cortical atrophy did not correlate with the psychological test score. The multi-infarct dementia patients differed from the controls in all CT variables including local changes. The SDAT patients had a more marked ventricular dilatation than the multi-infarct dementia patients. The multi-infarct dementia patients had more frequently local changes in SDAT patients. In the control group age correlated with ventricular dilatation, and the lower test scores correlated with cortical atrophy in the left temporal region.
对57例阿尔茨海默型老年痴呆症（SDAT）患者、19例多发梗死性痴呆患者以及85例年龄和性别相仿的对照者进行了计算机断层扫描（CT）检查。SDAT患者在脑室扩张、额角指数、中脑指数、第三脑室宽度以及皮质萎缩指数方面与对照者存在差异。即使是痴呆程度最轻的SDAT患者也与对照者不同。在SDAT组中，随着智力损害程度的加重，脑室扩张加剧，但皮质萎缩与心理测试得分无关。多发梗死性痴呆患者在所有CT变量（包括局部改变）方面均与对照者不同。SDAT患者的脑室扩张比多发梗死性痴呆患者更为明显。多发梗死性痴呆患者比SDAT患者更常出现局部改变。在对照组中，年龄与脑室扩张相关，较低的测试得分与左侧颞叶皮质萎缩相关。
Zotero 插件