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Enhancing effect of sodium taurocholate on N-methyl-N'-nitro-N-nitrosoguanidine-induced stomach tumorigenesis in rats.

作者信息

Kobori O, Watanabe J, Shimizu T, Shoji M, Morioka Y

出版信息

Gan. 1984 Aug;75(8):651-4.

PMID:6489675
Abstract

Male Wistar rats that had received a low dose of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and sodium taurocholate showed a significantly higher incidence of hyperplastic and neoplastic lesions in the stomach mucosa than did the MNNG-treated controls. The result suggested an enhancing effect of taurocholate in stomach tumorigenesis.

摘要

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