Jokipii L, Jokipii A M
Infection. 1978;6(2):92-4. doi: 10.1007/BF01642166.
Sixty patients with parasitologically confirmed giardiasis were treated with metronidazole using four different regimens administered to four groups of 15 patients each. A seven-day course of 200 mg thrice daily successfully eliminated the organism in 11 patients. A repetition of the seven-day course after an interval of one week was successful in 14 patients, a single dose of 2400 mg in nine patients, and two 2400 mg doses on successive days in 12 patients. Late relapses, detected more than one month after therapy, were relatively common in the single-dose groups. Side-effects associated with the 2400 mg dosages were frequent but tolerable.
60例经寄生虫学确诊的贾第虫病患者接受了甲硝唑治疗，采用四种不同方案，每组15例患者。每日三次服用200mg，疗程7天，成功清除病原体的有11例患者。间隔一周后重复7天疗程，14例患者治疗成功；单次服用2400mg，9例患者治疗成功；连续两天各服用2400mg，12例患者治疗成功。治疗一个多月后检测到的晚期复发在单剂量组中相对常见。与2400mg剂量相关的副作用频繁但可耐受。
