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毒扁豆碱对硬膜外吗啡引起的嗜睡的逆转作用。

The reversal of epidural morphine induced somnolence with physostigmine.

作者信息

Shulman M S, Sandler A, Brebner J

出版信息

Can Anaesth Soc J. 1984 Nov;31(6):678-80. doi: 10.1007/BF03008766.

DOI:10.1007/BF03008766
PMID:6498585
Abstract

Two case reports are presented of patients with post-thoracotomy pain treated with epidural morphine who developed somnolence several hours after the procedure. Physostigmine, 1 mg IV successfully reversed the somnolence without any effect on analgesia.

摘要

本文报告了两例开胸术后疼痛患者，采用硬膜外注射吗啡治疗，术后数小时出现嗜睡。静脉注射1毫克毒扁豆碱成功逆转了嗜睡，且对镇痛无任何影响。

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The reversal of epidural morphine induced somnolence with physostigmine.毒扁豆碱对硬膜外吗啡引起的嗜睡的逆转作用。
Can Anaesth Soc J. 1984 Nov;31(6):678-80. doi: 10.1007/BF03008766.
2
Effect of physostigmine on morphine-induced postoperative pain and somnolence.毒扁豆碱对吗啡诱导的术后疼痛和嗜睡的影响。
Br J Anaesth. 1982 Apr;54(4):429-34. doi: 10.1093/bja/54.4.429.
3
Post-thoracotomy analgesia: epidural vs intravenous morphine continuous infusion.开胸术后镇痛：硬膜外与静脉持续输注吗啡
Minerva Anestesiol. 2002 Sep;68(9):681-93.
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Continuous physostigmine combined with morphine-based patient-controlled analgesia in the postoperative period.术后持续使用毒扁豆碱联合基于吗啡的患者自控镇痛。
Acta Anaesthesiol Scand. 2005 Jan;49(1):78-84. doi: 10.1111/j.1399-6576.2004.00548.x.
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Epidural morphine as postoperative analgesic following cesarean section under epidural analgesia.剖宫产硬膜外镇痛术后使用硬膜外吗啡作为镇痛剂。
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Respiratory depression following epidural morphine: a clinical study.硬膜外注射吗啡后呼吸抑制：一项临床研究。
Can Anaesth Soc J. 1986 Sep;33(5):542-9. doi: 10.1007/BF03014258.

本文引用的文献

1
Effects of massive overdose of epidural morphine sulphate.大剂量硬膜外注射硫酸吗啡的影响。
Can Anaesth Soc J. 1982 Jul;29(4):377-80. doi: 10.1007/BF03007529.
2
Rostral spread of epidural morphine.硬膜外吗啡向头端扩散。
Anesthesiology. 1982 Jun;56(6):431-6. doi: 10.1097/00000542-198206000-00004.
3
Effect of physostigmine on morphine-induced postoperative pain and somnolence.毒扁豆碱对吗啡诱导的术后疼痛和嗜睡的影响。
Br J Anaesth. 1982 Apr;54(4):429-34. doi: 10.1093/bja/54.4.429.
4
Neurologic depression after intrathecal morphine.鞘内注射吗啡后的神经抑制
Anesthesiology. 1981 Jun;54(6):517-8. doi: 10.1097/00000542-198106000-00013.
5
Postthoracotomy pain and pulmonary function following epidural and systemic morphine.开胸术后硬膜外和全身应用吗啡后的疼痛及肺功能
Anesthesiology. 1984 Nov;61(5):569-75. doi: 10.1097/00000542-198411000-00017.
6
Physostigmine antagonizes morphine-induced respiratory depression in human subjects.毒扁豆碱可拮抗吗啡引起的人体呼吸抑制。
Anesthesiology. 1983 Jul;59(1):6-9. doi: 10.1097/00000542-198307000-00002.
7
The role of epidural morphine in the postcesarean patient: efficacy and effects on bonding.硬膜外吗啡在剖宫产术后患者中的作用：疗效及对母婴情感联结的影响。
Anesthesiology. 1983 Jun;58(6):500-4. doi: 10.1097/00000542-198306000-00003.
8
Spinal opiate analgesia: characteristics and principles of action.
Pain. 1981 Dec;11(3):293-346. doi: 10.1016/0304-3959(81)90633-3.
9
Early respiratory depression with epidural narcotic and intravenous droperidol.硬膜外使用麻醉剂和静脉注射氟哌利多后早期出现呼吸抑制。
Anesthesiology. 1983 Dec;59(6):559-60. doi: 10.1097/00000542-198312000-00014.
10
Opiate receptors and internal opiates.
Sci Am. 1977 Mar;236(3):44-56. doi: 10.1038/scientificamerican0377-44.