信号序列N端区域带电残基分布分析：对原核细胞和真核细胞中蛋白质输出的影响
Analysis of the distribution of charged residues in the N-terminal region of signal sequences: implications for protein export in prokaryotic and eukaryotic cells.
作者信息
von Heijne G
出版信息
EMBO J. 1984 Oct;3(10):2315-8. doi: 10.1002/j.1460-2075.1984.tb02132.x.
Abstract
A statistical analysis of the distribution of charged residues in the N-terminal region of 39 prokaryotic and 134 eukaryotic signal sequences reveals a remarkable similarity between the two samples, both in terms of net charge and in terms of the position of charged residues within the N-terminal region, and suggests that the formyl group on Metf is not removed in prokaryotic signal sequences.
摘要
对39个原核生物和134个真核生物信号序列N端区域带电残基分布的统计分析表明，这两个样本在净电荷以及N端区域内带电残基的位置方面都存在显著相似性，这表明原核生物信号序列中的甲硫氨酸上的甲酰基并未被去除。
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Analysis of the distribution of charged residues in the N-terminal region of signal sequences: implications for protein export in prokaryotic and eukaryotic cells.信号序列N端区域带电残基分布分析：对原核细胞和真核细胞中蛋白质输出的影响
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