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韦格纳肉芽肿病的严重肠道受累情况。

Severe intestinal involvement in Wegener's granulomatosis.

作者信息

Haworth S J, Pusey C D

出版信息

Gut. 1984 Nov;25(11):1296-300. doi: 10.1136/gut.25.11.1296.

DOI:10.1136/gut.25.11.1296
PMID:6500368
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1432325/
Abstract

A case of Wegener's granulomatosis is described, in which the presentation was blood stained mucus diarrhoea. Severe ileal, caecal, and rectal involvement improved rapidly after treatment with cyclophosphamide, azathioprine, and prednisolone. Although intestinal disease is an uncommon feature of Wegener's granulomatosis, both in our own experience (four of 45 cases) and in the literature, this diagnosis should be considered in view of the response to appropriate therapy.

摘要

本文描述了一例韦格纳肉芽肿病,其临床表现为血性黏液腹泻。经环磷酰胺、硫唑嘌呤和泼尼松龙治疗后,严重的回肠、盲肠和直肠病变迅速改善。尽管肠道疾病在韦格纳肉芽肿病中并不常见,无论是根据我们自己的经验(45例中有4例)还是文献报道,但鉴于对适当治疗的反应,应考虑作出这一诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d80/1432325/2aadd590f055/gut00396-0117-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d80/1432325/20e356a76c53/gut00396-0115-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d80/1432325/a7af24403100/gut00396-0115-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d80/1432325/b1c23f4cb6e3/gut00396-0116-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d80/1432325/2aadd590f055/gut00396-0117-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d80/1432325/20e356a76c53/gut00396-0115-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d80/1432325/a7af24403100/gut00396-0115-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d80/1432325/b1c23f4cb6e3/gut00396-0116-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d80/1432325/2aadd590f055/gut00396-0117-a.jpg

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Severe intestinal involvement in Wegener's granulomatosis.韦格纳肉芽肿病的严重肠道受累情况。
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本文引用的文献

1
Giant-cell granuloma of the respiratory tract (Wegener's granulomatosis).呼吸道巨细胞肉芽肿(韦格纳肉芽肿)
Br Med J. 1958 Aug 2;2(5091):265-70. doi: 10.1136/bmj.2.5091.265.
2
Wegener's granulomatosis: pathology and review of the literature.韦格纳肉芽肿病:病理学及文献综述
AMA Arch Pathol. 1954 Dec;58(6):533-53.
3
Wegener's granulomatosis.韦格纳肉芽肿病
环磷酰胺相关性肠炎致肉芽肿伴多血管炎患者发生严重蛋白丢失性肠病:一例报告。
World J Gastroenterol. 2021 May 28;27(20):2657-2663. doi: 10.3748/wjg.v27.i20.2657.
4
A Ruptured Jejunal Arterial Aneurysm in a Young Woman Undergoing Chronic Hemodialysis Due to Myeloperoxidase-antineutrophil Cytoplasmic Antibody-associated Vasculitis.年轻女性因髓过氧化物酶-抗中性粒细胞胞质抗体相关性血管炎而行慢性血液透析时发生肠动脉破裂性动脉瘤。
Intern Med. 2021 Sep 15;60(18):2939-2945. doi: 10.2169/internalmedicine.6721-20. Epub 2021 Mar 29.
5
Granulomatosis with polyangiitis with intestinal involvement successfully treated with rituximab and surgery.利妥昔单抗联合手术成功治疗累及肠道的肉芽肿性多血管炎
BMJ Case Rep. 2019 Aug 10;12(8):e230355. doi: 10.1136/bcr-2019-230355.
6
A rare endoscopic appearance of granulomatosis with polyangiitis involving the intestine: a case report.肉芽肿性多血管炎累及肠道的一种罕见内镜表现:病例报告
BMC Gastroenterol. 2018 Oct 25;18(1):154. doi: 10.1186/s12876-018-0885-9.
7
Granulomatosis with Polyangiitis Localized in the Greater Omentum.局限于大网膜的肉芽肿性多血管炎
Case Rep Surg. 2018 Feb 28;2018:6145903. doi: 10.1155/2018/6145903. eCollection 2018.
8
Granulomas in the gastrointestinal tract: deciphering the Pandora's box.胃肠道中的肉芽肿:开启潘多拉魔盒之谜
Virchows Arch. 2018 Jan;472(1):3-14. doi: 10.1007/s00428-017-2210-3. Epub 2017 Aug 4.
9
Gastrointestinal tract involvement in granulomatosis with polyangiitis.胃肠道受累于显微镜下多血管炎。
Prz Gastroenterol. 2016;11(4):270-275. doi: 10.5114/pg.2016.57887. Epub 2016 Feb 11.
10
Coexistence of granulomatosis with polyangiitis (GPA) and Crohn's disease or multiorgan manifestation of the same disease?肉芽肿性多血管炎(GPA)与克罗恩病并存,还是同一疾病的多器官表现?
Reumatologia. 2016;54(2):86-90. doi: 10.5114/reum.2016.60219. Epub 2016 Jun 3.
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4
Wegener's granulomatosis. Long-term results of treatment.韦格纳肉芽肿病。治疗的长期结果。
Ann Otol Rhinol Laryngol. 1981 May-Jun;90(3 Pt 1):231-5. doi: 10.1177/000348948109000307.
5
Small intestinal perforation in Wegener's granulomatosis.韦格纳肉芽肿病中的小肠穿孔
Postgrad Med J. 1982 Feb;58(676):123-5. doi: 10.1136/pgmj.58.676.123.
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7
Gastrointestinal manifestations of systemic vasculitis.系统性血管炎的胃肠道表现
Q J Med. 1983 Spring;52(206):141-9.
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Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.韦格纳肉芽肿病:85例患者21年的前瞻性临床与治疗经验
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