Pinegin B V, Klemparskaia N N, Mal'tsev V N, Korshunov V M, Shal'nova G A
Zh Mikrobiol Epidemiol Immunobiol. 1984 Sep(9):61-5.
In experiments on 4000 noninbred and CBA mice the influence of the injections of alpha-, beta- and gamma-globusin, IgG and IgM, obtained from the sera of hemostimulated and intact mice, on the intestinal microflora after irradiation has been studied. The experiments have revealed that 3 subcutaneous or intraperitoneal injections of 1 mg per mouse, made 2, 24 and 48 hours after the irradiation of the animals with gamma-rays in a dose of 700 r, considerably reduce the intensity of the accumulation of opportunistic bacteria in the small and large intestines, commonly occurring in irradiated animals. A decrease in the number of lactobacteria is less pronounced. The preparations of globulin and IgG obtained from hemostimulated mice, i.e. enriched with normal tissue antibodies, have proved to be most effective.
在对4000只非近交系和CBA小鼠进行的实验中，研究了从血液刺激和未受刺激小鼠血清中获取的α-、β-和γ-球蛋白、IgG和IgM注射剂对辐照后肠道微生物群的影响。实验表明，在动物接受700伦琴剂量的γ射线辐照后2、24和48小时，每只小鼠皮下或腹腔注射1毫克，共注射3次，可显著降低辐照动物小肠和大肠中机会性细菌的积累强度。乳酸菌数量的减少不太明显。从血液刺激小鼠中获得的富含正常组织抗体的球蛋白和IgG制剂被证明是最有效的。
