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[轻度颅脑创伤急性期的免疫学变化]

[Immunologic changes in the acute period of slight craniocerebral trauma].

作者信息

Morozov V V, Shangaĭ V A, Kovalevskaia T V

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1984 Sep-Oct(5):41-5.

PMID:6506992
Abstract

The authors discuss the results of a dynamic study of the characteristics of nonspecific immune responsiveness (properdin, total protein and globulin fractions in blood plasma, C-reactive protein, and immunoglobulins G, A, and M) as well as of the index of water metabolism of the brain matter--the antidiuretic hormone (ADH) in plasma, in 259 patients with the nosological forms of a mild craniocerebral injury 145 of whom had concussion of the brain and 105 had mild contusion of the brain. Congruence of the clinical manifestations of the injury and the level of plasma ADH was recorded. The participation of the factors of nonspecific immune responsiveness in the body compensatory posttraumatic reactions and the genesis of the clinical manifestations of a mild craniocerebral injury is emphasized.

摘要

作者探讨了对259例患有轻度颅脑损伤不同病种的患者进行的一项动态研究结果,该研究涉及非特异性免疫反应性特征(血浆中的备解素、总蛋白和球蛋白组分、C反应蛋白以及免疫球蛋白G、A和M)以及脑物质水代谢指标——血浆中的抗利尿激素(ADH)。其中145例为脑震荡,105例为轻度脑挫伤。记录了损伤的临床表现与血浆ADH水平的一致性。强调了非特异性免疫反应性因素在机体创伤后代偿反应以及轻度颅脑损伤临床表现发生过程中的作用。

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