伯明翰市亚洲人的冠状动脉疾病
Coronary artery disease in Asians in Birmingham.
作者信息
Lowry P J, Glover D R, Mace P J, Littler W A
出版信息
Br Heart J. 1984 Dec;52(6):610-3. doi: 10.1136/hrt.52.6.610.
Abstract
The severity and pattern of coronary artery disease in patients referred for investigation of the disease was compared between Asian and white patients living in Birmingham, matched for age, sex, blood pressure, and duration of symptoms, to investigate the clinical impression that Asians have worse, in particular worse distal, coronary artery disease than whites. Risk factors and outcome were also examined. The coronary angiograms of 34 Asians were compared blindly and repeatedly with those of 68 whites by two independent observers. Coronary artery disease was found to be quantitatively more severe in Asians, but the distribution of the disease was the same. Some risk factors were significantly different: fewer Asians were smokers; fasting cholesterol concentrations were higher in whites; and whites were heavier, with a larger body surface area. Follow up data showed that more Asians were refused coronary artery bypass surgery because of the severity of their disease.
摘要
为调查关于亚洲人比白人患有更严重，尤其是更严重的远端冠状动脉疾病这一临床印象，对居住在伯明翰且年龄、性别、血压和症状持续时间相匹配的亚洲患者和白人患者进行疾病调查时所患冠状动脉疾病的严重程度和模式进行了比较。还对危险因素和结果进行了检查。两名独立观察者对34名亚洲人的冠状动脉造影与68名白人的冠状动脉造影进行了盲法反复比较。发现亚洲人的冠状动脉疾病在数量上更为严重，但疾病分布相同。一些危险因素存在显著差异：吸烟的亚洲人较少；白人的空腹胆固醇浓度较高；白人更重，体表面积更大。随访数据显示，更多亚洲人因疾病严重程度而被拒绝进行冠状动脉搭桥手术。
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