Larrey D, Rueff B, Feldmann G, Degott C, Danan G, Benhamou J P
Gut. 1984 Dec;25(12):1414-5. doi: 10.1136/gut.25.12.1414.
The existence of jaundice induced by hyperemesis gravidarum is controversial. We report the case of a woman who suffered from three episodes of jaundice during the first trimester of three consecutive pregnancies, a few days after the onset of hyperemesis gravidarum. Jaundice was caused by conjugated hyperbilirubinaemia. Serum alanine aminotransferase activity was increased and scarce necrotic hepatocytes were shown on light and electron microscopic examinations. Cessation of vomiting was rapidly followed by complete recovery. This observation supports the view that severe vomiting can cause jaundice in pregnant women.
妊娠剧吐所致黄疸的存在存在争议。我们报告一例妇女，在连续三次妊娠的孕早期，妊娠剧吐发作几天后，出现了三次黄疸发作。黄疸由结合胆红素血症引起。血清丙氨酸转氨酶活性升高，光镜和电镜检查显示肝细胞坏死少见。呕吐停止后迅速完全恢复。该观察结果支持严重呕吐可导致孕妇黄疸的观点。
