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环孢菌素A在建立爱泼斯坦-巴尔病毒转化的人淋巴母细胞系中的应用。

Use of cyclosporin A in establishing Epstein-Barr virus-transformed human lymphoblastoid cell lines.

作者信息

Anderson M A, Gusella J F

出版信息

In Vitro. 1984 Nov;20(11):856-8. doi: 10.1007/BF02619631.

DOI:10.1007/BF02619631
PMID:6519667
Abstract

We have investigated the potential for using cyclosporin A to increase the efficiency with which Epstein-Barr virus-transformed human lymphoblast lines can be prepared. Use of this immunosuppressive drug has permitted the development of a procedure with success rates exceeding 95% despite the processing of very large numbers of samples.

摘要

我们研究了使用环孢素A提高制备爱泼斯坦-巴尔病毒转化的人淋巴母细胞系效率的可能性。尽管处理了大量样本,但使用这种免疫抑制药物已使一种成功率超过95%的方法得以开发。

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Use of cyclosporin A in establishing Epstein-Barr virus-transformed human lymphoblastoid cell lines.环孢菌素A在建立爱泼斯坦-巴尔病毒转化的人淋巴母细胞系中的应用。
In Vitro. 1984 Nov;20(11):856-8. doi: 10.1007/BF02619631.
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Differential effects of cyclosporin-A on lymphocyte subpopulations.
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Nature. 1983;306(5940):234-8. doi: 10.1038/306234a0.
3
Cyclosporin A promotes spontaneous outgrowth in vitro of Epstein-Barr virus-induced B-cell lines.环孢菌素A促进爱泼斯坦-巴尔病毒诱导的B细胞系在体外的自发生长。
Nature. 1981 Jan 22;289(5795):300-1. doi: 10.1038/289300a0.
常染色体显性范科尼综合征患者因杂合P341L变异导致血浆中胍基乙酸减少及类器官治疗研究
JIMD Rep. 2024 Aug 19;65(5):341-353. doi: 10.1002/jmd2.12442. eCollection 2024 Sep.
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Human ITGAV variants are associated with immune dysregulation, brain abnormalities, and colitis.人类 ITGAV 变异与免疫失调、大脑异常和结肠炎有关。
J Exp Med. 2024 Dec 2;221(12). doi: 10.1084/jem.20240546. Epub 2024 Nov 11.
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Splice modulators target PMS1 to reduce somatic expansion of the Huntington's disease-associated CAG repeat.剪接调节剂靶向 PMS1 以减少亨廷顿病相关 CAG 重复的体细胞扩增。
Nat Commun. 2024 Apr 12;15(1):3182. doi: 10.1038/s41467-024-47485-0.
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Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data.从单细胞多组学数据中以细胞类型分辨率绘制疾病调控回路。
Nat Comput Sci. 2023 Jul;3(7):644-657. doi: 10.1038/s43588-023-00476-5. Epub 2023 Jul 25.
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Unsupervised contrastive peak caller for ATAC-seq.无监督对比峰 caller 用于 ATAC-seq。
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