von Deimling O H, Wassmer B, Müller M
Biochem Genet. 1984 Dec;22(11-12):1119-26. doi: 10.1007/BF00499636.
Genetic variation of a codominantly inherited esterase, designated ES-26, has been discovered in the house mouse using isoelectric focusing in polyacrylamide gels. The ES-26A phenotype (pI 8.2) was found in C57BL/10Sn. A/J showed the ES-26B phenotype (pI 7.8-7.9). A third phenotype, ES-26C (double-banded: pI's 8.1 and 8.3), was observed in SJL/J. ES-26 was detected only in liver, stomach, and small intestine. The enzyme was shown to be controlled by the presumed structural locus Es-26, located on chromosome 3. From a four-point cross, the gene order Car-2--6.2 +/- 2.7--Es-16--21.0 +/- 4.5--Es-26--13.6 +/- 3.8--Amy-1 was established.
利用聚丙烯酰胺凝胶等电聚焦技术，在家鼠中发现了一种共显性遗传酯酶（命名为ES - 26）的遗传变异。在C57BL/10Sn中发现了ES - 26A表型（等电点8.2）。A/J表现出ES - 26B表型（等电点7.8 - 7.9）。在SJL/J中观察到第三种表型ES - 26C（双带：等电点8.1和8.3）。ES - 26仅在肝脏、胃和小肠中检测到。该酶显示受位于3号染色体上的假定结构基因座Es - 26控制。通过四点杂交，确定了基因顺序为Car - 2--6.2 ± 2.7--Es - 16--21.0 ± 4.5--Es - 26--13.6 ± 3.8--Amy - 1。
