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[烟酸新衍生物烟酸锂的应激保护特性]

[Stress-protective properties of lithium nicotinate--a new derivative of nicotinic acid].

作者信息

Kresiun V I

出版信息

Biull Eksp Biol Med. 1984 Mar;97(3):312-5.

PMID:6538449
Abstract

Experiments were made to study stress-protective properties of a new psychotropic agent lithium nicotinate developed on the basis of natural metabolites. Prophylactic treatment of the drug given in courses entails an increase in the physical endurance and work fitness, improvement of animals' orientation under stress, facilitating the avoidance behavior. These effects were particularly demonstrable in highly emotional animals. In these animals, stress produced a paralyzing action. According to the electro- and ballisto-cardiography, the drug prevented the stress-induced disorders of cardiovascular function.

摘要

开展了实验以研究一种基于天然代谢产物研发的新型精神药物烟酸锂的应激保护特性。该药物进行疗程预防性治疗能提高身体耐力和工作适应性,改善动物在应激状态下的定向能力,促进回避行为。这些效应在高度情绪化的动物中尤为明显。在这些动物中,应激会产生麻痹作用。根据心电图和心冲击图,该药物可预防应激诱导的心血管功能紊乱。

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