Chanas A C, Johnson B K, Simpson D I
J Gen Virol. 1976 Aug;32(2):295-300. doi: 10.1099/0022-1317-32-2-295.
A cross-neutralization study of 22 alphaviruses disclosed two major antigenic complexes and two viruses that were distinct from all the others. Cross-reactions were common but were restricted within the complexes. Sub-groupings within a complex were also shown, and some viruses proved to be indistinguishable by neutralization testing. The results generally paralleled previously reported data. Investigations were carried out, using BHK 2I cells in a micro tissue-culture system, on all available alphaviruses.
一项对22种甲病毒的交叉中和研究揭示了两个主要抗原复合物以及两种与其他所有病毒都不同的病毒。交叉反应很常见，但局限于复合物内部。复合物内部也显示出亚分组情况，并且一些病毒经中和试验证明无法区分。结果总体上与先前报告的数据相符。在微组织培养系统中使用BHK 2I细胞，对所有可得的甲病毒进行了研究。
