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通过中和反应研究本扬韦拉病毒群病毒之间的关系。

Relationships of bunyamwera group viruses by neutralization.

作者信息

Hunt A R, Calisher C H

出版信息

Am J Trop Med Hyg. 1979 Jul;28(4):740-9.

PMID:464195
Abstract

A standardized serum dilution plaque reduction neutralization test was used for cross-neutralization studies of 23 strains of Bunyamwera serogroup viruses. Antigenic relationships were determined by inspection of the neutralization tests results as well as by numerical taxonomic analysis. Based on these analyses five complexes, containing 1-11 viruses, were distinguished. Little or no cross-reactivity was observed between viruses of different complexes. Three of the viruses tested were indistinguishable from prototypes and probably represent strains or varieties of those prototypes. A tentative classification scheme for the Bunyamwera group is presented.

摘要

采用标准化血清稀释蚀斑减少中和试验,对23株本扬韦拉血清群病毒进行交叉中和研究。通过检查中和试验结果以及数值分类分析来确定抗原关系。基于这些分析,区分出了五个复合物,每个复合物包含1至11种病毒。不同复合物的病毒之间几乎没有或没有观察到交叉反应性。所测试的三种病毒与原型无法区分,可能代表那些原型的菌株或变种。提出了本扬韦拉病毒群的暂定分类方案。

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