Besson F, Michel G
J Antibiot (Tokyo). 1984 Jun;37(6):646-51. doi: 10.7164/antibiotics.37.646.
The action of iturin A and bacillomycin L on vesicles of dipalmitoylphosphatidylcholine (DPPC) and DPPC-cholesterol was studied. Iturin A destroyed the vesicles, bacillomycin L bound with DPPC vesicles and destroyed vesicles containing DPPC and cholesterol. These results are discussed in comparison with the action of antibiotics of the iturin group on cytoplasmic membranes.
研究了伊枯草菌素A和杆菌霉素L对二棕榈酰磷脂酰胆碱(DPPC)囊泡以及DPPC - 胆固醇囊泡的作用。伊枯草菌素A破坏了囊泡,杆菌霉素L与DPPC囊泡结合并破坏了含有DPPC和胆固醇的囊泡。将这些结果与伊枯草菌素组抗生素对细胞质膜的作用进行了比较讨论。