Pylkkänen J
Acta Paediatr Scand. 1978 May;67(3):275-9. doi: 10.1111/j.1651-2227.1978.tb16320.x.
The presence of antibody-coated bacteria in urine has been shown to be an indicator for renal bacteriuria in adults with chronic UTI. To evaluate this method (ABCU test) in pediatric patients, 128 infants and children with their first UTI were investigated. Twenty-nine patients of the 78 who had a first clinically defined upper UTI had antibody-coated bacteria in urine. The test was seldom (2/20) positive in the infants under six months. In the older patients (27/58 ABCU-positive) the frequency of positive tests increased with the duration of symptoms. When the symptoms had lasted for over one weeks, 11 out of the 13 children with their first upper UTI showed antibody-coated bacteria in urine. Four of the 36 first lower UTIs and 5 out of the 14 asymptomatic cases were ABCU-positive. The patients were followed-up for an average of 9 months. Those who were classified as having first upper UTI had in most cases a positive ABCU test in recurrences, independently of the clinical picture. The recurrences after the first lower UTIs showed antibody-coated bacteria in urine only when the recurrence was classified as upper UTI on the grounds of the clinical criteria used.
尿中存在抗体包被细菌已被证明是慢性尿路感染成年患者肾菌尿的一个指标。为评估该方法（ABCU试验）在儿科患者中的应用，对128例首次发生尿路感染的婴幼儿和儿童进行了研究。在78例首次临床诊断为上尿路感染的患者中，有29例尿中存在抗体包被细菌。6个月以下婴儿该试验很少呈阳性（2/20）。在年龄较大的患者中（27/58 ABCU阳性），阳性试验的频率随症状持续时间增加。当症状持续超过1周时，13例首次发生上尿路感染的儿童中有11例尿中出现抗体包被细菌。36例首次发生下尿路感染的患者中有4例、14例无症状病例中有5例ABCU阳性。对患者平均随访9个月。那些被分类为首次发生上尿路感染的患者在复发时多数ABCU试验呈阳性，与临床表现无关。首次发生下尿路感染后的复发仅在根据所用临床标准分类为上尿路感染时尿中才出现抗体包被细菌。
