Waugh M A, Evans E G, Nayyar K C, Fong R
Br J Vener Dis. 1978 Jun;54(3):184-6. doi: 10.1136/sti.54.3.184.
Clotrimazole 1% (Canesten) cream was used in a trial comprising 138 men with candidal balanitis. Eighty-six (91%) out of 94 men were asymptomatic after seven days and 57 (98%) of 58 men were asymptomatic after three weeks' treatment. After seven days, Candida albicans could no longer be cultured from 86 (90%) of 96 men, nor from 55 (95%) of 58 men three weeks after treatment. Microscopical examination gave varying results. Fifteen (10.9%) of 138 men were found to have diabetes mellitus; this group was significantly older than the non-diabetics. It is concluded that treatment with clotrimazole for seven days is effective in the treatment of candidal balanitis.
1%克霉唑(凯妮汀)乳膏用于一项包含138例念珠菌性龟头炎男性患者的试验。94例男性患者中有86例(91%)在7天后无症状,58例男性患者中有57例(98%)在治疗3周后无症状。治疗7天后,96例男性患者中有86例(90%)的白色念珠菌无法培养出来,治疗3周后,58例男性患者中有55例(95%)的白色念珠菌无法培养出来。显微镜检查结果各异。138例男性患者中有15例(10.9%)被发现患有糖尿病;该组患者明显比非糖尿病患者年龄大。得出的结论是,克霉唑治疗7天对念珠菌性龟头炎有效。