Torczynski R, Bollon A P, Fuke M
Mol Gen Genet. 1983;191(3):427-9. doi: 10.1007/BF00425758.
The 5'-terminal 597 base-pairs (bp) of the Sprague-Dawley rat 18S ribosomal RNA gee and 10 bp of the adjoining transcribed spacer have been sequenced. Previously sequenced 10 large oligonucleotides of rat 18S RNA were located in this region. This mammalian sequence has been compared with the known sequences of yeast and frog 18S rDNA's. The analysis indicates that 534 bp of the 597 bp (89%) are conserved between rat and frog sequences but only 75% of the nucleotides are conserved between rat and yeast in this region. Two large and two small sections have been identified where insertions have been introduced during evolution. Of these 58 bp long inserted sections of the rat rDNA sequence, 50 bp (86%) were G-C base-pairs.
已对斯普拉格 - 道利大鼠18S核糖体RNA基因的5'末端597个碱基对（bp）以及相邻转录间隔区的10个bp进行了测序。先前测序的大鼠18S RNA的10个大的寡核苷酸位于该区域。已将该哺乳动物序列与酵母和青蛙18S rDNA的已知序列进行了比较。分析表明，大鼠和青蛙序列之间597 bp中的534 bp（89%）是保守的，但在该区域大鼠和酵母之间只有75%的核苷酸是保守的。已鉴定出两个大的和两个小的区域，在进化过程中引入了插入序列。在大鼠rDNA序列的这些58 bp长的插入区域中，50 bp（86%）是G - C碱基对。
