古巴人群中HLA抗原的分布情况。

Distribution of HLA antigens in a Cuban population.

作者信息

Díaz J W, Cheredeev A N

出版信息

Tissue Antigens. 1977 Feb;9(2):71-9. doi: 10.1111/j.1399-0039.1977.tb01085.x.

DOI:10.1111/j.1399-0039.1977.tb01085.x

Abstract

The frequencies of the HLA antigens were determined in a population of 160 unrelated Cubans from three different ethnic groups (white, mixed-blood and negro). We typed for antigenic specificities of the A and B loci, and also for the Cw1 specificity of the C locus. Phenotype and gene frequencies for the different ethnic groups are presented for comparison. The phenotype distribution, the haplotype frequencies for the white group and the genetic distance between this group and a Spanish population were calculated.

摘要

在来自三个不同种族群体（白人、混血和黑人）的160名无亲缘关系的古巴人群体中，测定了HLA抗原的频率。我们对A和B位点的抗原特异性进行了分型，同时也对C位点的Cw1特异性进行了分型。列出了不同种族群体的表型和基因频率以供比较。计算了白人组的表型分布、单倍型频率以及该组与西班牙人群体之间的遗传距离。