在相对低场强（1.9 T）下通过1H核磁共振在体内检测低氧血症期间的脑乳酸。
Detection of cerebral lactate in vivo during hypoxemia by 1H NMR at relatively low field strengths (1.9 T).
作者信息
Behar K L, Rothman D L, Shulman R G, Petroff O A, Prichard J W
出版信息
Proc Natl Acad Sci U S A. 1984 Apr;81(8):2517-9. doi: 10.1073/pnas.81.8.2517.
Abstract
1H NMR was used to monitor lactate production and clearance during hypoxemia and recovery in the rabbit brain at the relatively low magnetic-field strength of 1.89 T. An array of conventional physiological variables were recorded simultaneously with spectrum acquisition, including the electroencephalogram and electrocardiogram. The sensitivity and spectral resolution achieved at this field strength should be applicable to studies of human brain pathophysiology in the large-bore magnets now available.
摘要
在1.89 T的相对低磁场强度下，利用1H核磁共振（1H NMR）监测兔脑在低氧血症期间及恢复过程中的乳酸生成和清除情况。在采集光谱的同时，还同步记录了一系列传统生理变量，包括脑电图和心电图。在这种场强下实现的灵敏度和光谱分辨率应该适用于目前可用的大孔径磁体中对人脑病理生理学的研究。
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