肾病患者的自体玫瑰花结形成细胞

Autologous rosette forming cells in patients with renal diseases.

作者信息

Kuramochi T, Ohnuki T, Inoue T, Ishida M

出版信息

Clin Exp Immunol. 1983 Dec;54(3):765-70.

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1536168/

Abstract

We studied the distribution of autologous rosette forming cells (ARFC) in the peripheral blood of 30 healthy adult donors, 30 patients with IgA nephropathy, 20 patients with primary glomerular diseases, eight patients with systemic diseases and 25 patients with other renal diseases. The mean percentages of ARFC were markedly reduced in the IgA nephropathy patients compared with the healthy adult donors. The values for ARFC were even more significantly reduced in IgA nephropathy patients compared with patients with primary glomerular diseases, systemic diseases and other renal diseases. This means that the immunoregulatory abberation in IgA nephropathy primarily involves T cells.

摘要

我们研究了30名健康成年献血者、30名IgA肾病患者、20名原发性肾小球疾病患者、8名全身性疾病患者和25名其他肾脏疾病患者外周血中自体花环形成细胞（ARFC）的分布情况。与健康成年献血者相比，IgA肾病患者的ARFC平均百分比显著降低。与原发性肾小球疾病患者、全身性疾病患者和其他肾脏疾病患者相比，IgA肾病患者的ARFC值降低得更为显著。这意味着IgA肾病中的免疫调节异常主要涉及T细胞。

相似文献

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Characterization of autologous rosette-forming cells: a nonrestricted phenomenon.

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Role of the autologous rosette-forming T cells in the concanavalin A-induced suppressor cell function.

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Increase of IgA specific helper T alpha cells in patients with IgA nephropathy.IgA 肾病患者中 IgA 特异性辅助性 Tα 细胞增加。

Clin Exp Immunol. 1982 Oct;50(1):77-82.

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The red-cell immune system.

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