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肾病患者的自体玫瑰花结形成细胞

Autologous rosette forming cells in patients with renal diseases.

作者信息

Kuramochi T, Ohnuki T, Inoue T, Ishida M

出版信息

Clin Exp Immunol. 1983 Dec;54(3):765-70.

PMID:6606516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1536168/
Abstract

We studied the distribution of autologous rosette forming cells (ARFC) in the peripheral blood of 30 healthy adult donors, 30 patients with IgA nephropathy, 20 patients with primary glomerular diseases, eight patients with systemic diseases and 25 patients with other renal diseases. The mean percentages of ARFC were markedly reduced in the IgA nephropathy patients compared with the healthy adult donors. The values for ARFC were even more significantly reduced in IgA nephropathy patients compared with patients with primary glomerular diseases, systemic diseases and other renal diseases. This means that the immunoregulatory abberation in IgA nephropathy primarily involves T cells.

摘要

我们研究了30名健康成年献血者、30名IgA肾病患者、20名原发性肾小球疾病患者、8名全身性疾病患者和25名其他肾脏疾病患者外周血中自体花环形成细胞（ARFC）的分布情况。与健康成年献血者相比，IgA肾病患者的ARFC平均百分比显著降低。与原发性肾小球疾病患者、全身性疾病患者和其他肾脏疾病患者相比，IgA肾病患者的ARFC值降低得更为显著。这意味着IgA肾病中的免疫调节异常主要涉及T细胞。

相似文献

1
Autologous rosette forming cells in patients with renal diseases.肾病患者的自体玫瑰花结形成细胞
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本文引用的文献

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Immune aspects of renal diseases.肾脏疾病的免疫方面。
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Increase in rosette-forming T cells with autologous human erythrocytes in lymphocytes of patients with tuberculosis by in vitro stimulation with purified protein derivative.通过用纯化蛋白衍生物进行体外刺激，结核病患者淋巴细胞中与自体人红细胞形成花环的T细胞增加。
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Human autologous rosettes. II. Further characterization: markers and functions.人自体玫瑰花结。II. 进一步的特性描述：标志物与功能。
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IgA-specific helper activity of T alpha cells in human peripheral blood.人外周血中Tα细胞的IgA特异性辅助活性。
J Immunol. 1981 Dec;127(6):2612-3.
5
Human post-thymic precursor cells in health and disease. IX. Immunoregulatory T cell circuits in peripheral blood of patients with rheumatoid arthritis.健康与疾病状态下的人类胸腺后前体细胞。IX. 类风湿关节炎患者外周血中的免疫调节性T细胞回路
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6
Separation of concanavalin A-induced human suppressor and helper T cells by the autologous erythrocyte rosette technique.用自身红细胞花环技术分离伴刀豆球蛋白A诱导的人抑制性和辅助性T细胞
J Clin Invest. 1981 Aug;68(2):447-53. doi: 10.1172/jci110274.
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Characterization of autologous rosette-forming cells: a nonrestricted phenomenon.
J Immunol. 1981 Aug;127(2):737-41.
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Role of the autologous rosette-forming T cells in the concanavalin A-induced suppressor cell function.自体玫瑰花结形成T细胞在刀豆球蛋白A诱导的抑制细胞功能中的作用。
Cell Immunol. 1981 Jul 1;61(2):273-9. doi: 10.1016/0008-8749(81)90375-0.
9
Increase of IgA specific helper T alpha cells in patients with IgA nephropathy.IgA 肾病患者中 IgA 特异性辅助性 Tα 细胞增加。
Clin Exp Immunol. 1982 Oct;50(1):77-82.
10
The red-cell immune system.红细胞免疫系统
Lancet. 1981 Sep 12;2(8246):556-9. doi: 10.1016/s0140-6736(81)90941-7.

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