金黄色葡萄球菌中介导庆大霉素耐药性的接合质粒的比较分析。
Comparative analysis of conjugative plasmids mediating gentamicin resistance in Staphylococcus aureus.
作者信息
Goering R V, Ruff E A
出版信息
Antimicrob Agents Chemother. 1983 Sep;24(3):450-2. doi: 10.1128/AAC.24.3.450.
Abstract
Five gentamicin-resistant clinical isolates of Staphylococcus aureus were found to contain self-transmissible plasmids of 32 to 37 megadaltons in size. Restriction endonuclease digests of the plasmids were markedly similar to those of reference plasmids of unrelated geographical origin, thus suggesting the significant contribution of common conjugal plasmids to the emergence of gentamicin resistance in S. aureus populations.
摘要
发现五株耐庆大霉素的金黄色葡萄球菌临床分离株含有大小为32至37兆道尔顿的自我传递质粒。这些质粒的限制性内切酶消化产物与来自不同地理区域的参考质粒的消化产物明显相似，这表明常见的接合质粒对金黄色葡萄球菌群体中庆大霉素耐药性的出现有重大贡献。
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