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脊髓创伤性空洞形成的病理生理机制。

Pathophysiological mechanism of traumatic cavitation of the spinal cord.

作者信息

Wozniewicz B, Filipowicz K, Swiderska S K, Deraka K

出版信息

Paraplegia. 1983 Oct;21(5):312-7. doi: 10.1038/sc.1983.52.

Abstract

The gross anatomy and the histological appearances of the spinal cord were studied in 120 patients who died in the Metropolitan Rehabilitation Centre at Konstancin as a result of a spinal injury. Three varieties of lesion were found: Total disorganisation of the spinal cord at the site of trauma. Total disorganisation of the cord at the site of trauma associated with pipelike necrosis extending up and down from the main injury. This longitudinal cylindrical-pipelike necrosis is described in this paper as 'traumatic haemorrhagic cavitation'. Partial spinal cord necrosis localised to the area of supply of intraspinal arteries. The possible vascular mechanisms of traumatic spinal cord injury, resembling the changes observed in experimental animals, are discussed.

摘要

对120名在康斯坦钦市大都会康复中心因脊髓损伤死亡的患者的脊髓大体解剖和组织学表现进行了研究。发现了三种病变类型:创伤部位脊髓完全紊乱;创伤部位脊髓完全紊乱,伴有从主要损伤处向上和向下延伸的管状坏死。本文将这种纵向圆柱形管状坏死描述为“创伤性出血性空洞”;脊髓部分坏死局限于脊髓内动脉供血区域。文中讨论了创伤性脊髓损伤可能的血管机制,这些机制类似于在实验动物中观察到的变化。

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