Jarvis M J, Russell M A, Feyerabend C
Thorax. 1983 Nov;38(11):829-33. doi: 10.1136/thx.38.11.829.
Seven non-smokers were exposed to tobacco smoke under natural conditions for two hours in a public house. Measures of nicotine and cotinine in plasma, saliva, and urine and expired air carbon monoxide all showed reliable increases. The concentrations of carbon monoxide and nicotine after exposure averaged 15.7% and 7.5% respectively of the values found in heavy smokers. Although the increase in expired air carbon monoxide of 5.9 ppm was similar to increases in smokers after a single cigarette, the amount of nicotine absorbed was between a tenth and a third of the amount taken in from one cigarette. Since this represented a relatively extreme acute natural exposure, any health risks of passive smoking probably depend less on quantitative factors than on qualitative differences between sidestream and mainstream smoke.
七名不吸烟者在一家酒馆的自然环境中接触了两小时的烟草烟雾。血浆、唾液、尿液中的尼古丁和可替宁含量以及呼出气体中的一氧化碳含量均出现了可靠的增加。接触后一氧化碳和尼古丁的浓度分别平均为重度吸烟者所测值的15.7%和7.5%。虽然呼出气体中一氧化碳增加5.9 ppm与吸烟者吸一支烟后的增加量相似，但吸收的尼古丁量仅为吸一支烟所摄入尼古丁量的十分之一到三分之一。由于这代表了一种相对极端的急性自然暴露情况，被动吸烟的任何健康风险可能更多地取决于侧流烟和主流烟之间的质量差异，而非数量因素。
