通过31P核磁共振观察灌注心脏中的第二个磷酸池；这是线粒体磷酸吗？
Observation of a second phosphate pool in the perfused heart by 31P NMR; is this the mitochondrial phosphate?
作者信息
Garlick P B, Brown T R, Sullivan R H, Ugurbil K
出版信息
J Mol Cell Cardiol. 1983 Dec;15(12):855-8. doi: 10.1016/0022-2828(83)90347-4.
PMID:6663633
Abstract
We report here our observations on perfused rat hearts using 31P NMR which show that inorganic phosphate (Pi) is located in two regions of differing pH. From the chemical shifts of the Pi signals and their behaviour under various stimuli we identify one signal (pH 7.0) as coming from the cytosol and suggest that the other (pH 7.38) comes from the mitochondrial matrix space.
摘要
我们在此报告利用31P核磁共振技术对灌注大鼠心脏进行观察的结果，这些结果表明无机磷酸盐（Pi）位于两个pH值不同的区域。根据Pi信号的化学位移及其在各种刺激下的表现，我们确定其中一个信号（pH 7.0）来自细胞质，并推测另一个信号（pH 7.38）来自线粒体基质空间。
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