Rohr K R, Rooney J A
Biophys J. 1978 Jul;23(1):33-40. doi: 10.1016/S0006-3495(78)85430-7.
The effects of continuous wave ultrasound at a frequency of 1 MHz in the intensity range of 0-1.4 W/cm2 on an oxidized cholesterol bilayer lipid membrane (BLM) were observed. Ultrasound at 1.5 W/cm2 broke the membrane; in the range from 0.5 to 1.4 W/cm2, it accelerated the draining of the bulk lipid solution from the annulus to the Teflon support. At all intensities it has no effect on the conductance, the capacitance, or the dependence of each on the voltage applied across the membrane. Electrical parameters were measured in the presence of aqueous solutions of NaCl, KCl, and distilled water. The motivation and results of this project are explained in relation to an overall objective of determining the specific effects of ultrasound on biological membranes.
观察了频率为1兆赫、强度范围在0 - 1.4瓦/平方厘米的连续波超声对氧化胆固醇双层脂质膜（BLM）的影响。1.5瓦/平方厘米的超声会破坏膜；在0.5至1.4瓦/平方厘米范围内，它会加速大量脂质溶液从环隙排向聚四氟乙烯支撑体。在所有强度下，超声对电导、电容以及它们各自对跨膜施加电压的依赖性均无影响。在氯化钠、氯化钾水溶液和蒸馏水存在的情况下测量了电学参数。结合确定超声对生物膜的特定影响这一总体目标，对该项目的动机和结果进行了解释。
